I-55 Hotels in Missouri

North-South Interstate Between Chicago and New Orleans

I-55 Road Trip Hotels In Missouri Cities and Towns

St. Louis, MO Hotels

I-55 cross the Mississippi River into St. Louis just a block south of the Gateway Arch


St. Louis to Festus: 33 miles


Festus to Perryville: 46 miles


Perryville to Cape Girardeau: 33 miles


Cape Girardeau to Sikeston: 29 miles


Sikeston to Hayti: 48 miles

I-55 States

Arkansas
Illinois
Louisiana
Missouri
Mississippi
Tennessee

Recent Updates

Hampton Inn & Suites Bessemer Birmingham

Hampton Inn on the southern end of the Birmingham metro area gets great reviews

BAGSMART Toiletry Travel Bag

The easy way to keep your toiletries organized when traveling - in 12 different colors! #ad

Holiday Inn Express Westley

A place to stay on one of those long road trips on I-5 through California

Holiday Inn Express Hotel & Suites Pell City

Hotel is on the north side of Pell City, at the town's exit off I-20 in eastern Alabama

Holiday Inn Express & Suites Willcox

Hotel on I-10 in New Mexico, on the long ride from Texas to the Pacific Coast

BAGAIL Compression Packing Cubes

Save space and keep things organized when traveling #ad

Fairfield Inn & Suites by Marriott Stony Creek

Comfortable road trip hotel adjacent to I-95 in southern Virginia