I-22 Hotels in Mississippi

I-22 Road Trip Hotels In Mississippi Cities and Towns

Fulton to Tupelo: 18 miles

Tupelo to New Albany: 26 miles

New Albany to Holly Springs: 31 miles

Holly Springs to Byhalia: 18 miles

The west end of I-22 is where it meets I-269 on the southeast side of the Memphis area

Hampton Inn on the southern end of the Birmingham metro area gets great reviews

The easy way to keep your toiletries organized when traveling - in 12 different colors! #ad

A place to stay on one of those long road trips on I-5 through California

Hotel is on the north side of Pell City, at the town's exit off I-20 in eastern Alabama

Hotel on I-10 in New Mexico, on the long ride from Texas to the Pacific Coast

Just the right size to get you through the TSA checkpoint without a hassle #ad

Comfortable road trip hotel adjacent to I-95 in southern Virginia