I-59 Hotels

From Louisiana to Georgia via Mississippi and Alabama

I-59 is a north-south interstate highway of just under 450 miles that connects the northwest corner of Georgia with southeastern Louisiana. The north end of the road is just a few miles south of Chattanooga, Tennessee and the southern end is about 30 miles from the center of New Orleans.

The largest city along the route of I-59 is Birmingham, Alabama, where it intersects with several other interstate highways: I-20, I-22 and I-65. I-59 shares the road with I-20 for the 146 miles between Birmingham and Meridian, Mississippi.

Road Trip Hotels In I-59 Cities and Towns

Junction of I-59 and I-24, GA

The north end of I-59 is at a junction with I-24 in the northwest corner of Georgia
Birmingham: 136 miles


Junction of I-59 and I-24 to Trenton: 9 miles

Trenton, GA

City/town on I-59 with hotels
Birmingham: 127 miles


Trenton to Fort Payne: 34 miles

Fort Payne, AL

City/town on I-59 with hotels
Birmingham: 93 miles


Fort Payne to Gadsden: 38 miles

Gadsden, AL

Attalla is on the west side of Gadsden, Alabama
Birmingham: 55 miles


Gadsden to Springville: 27 miles

Springville, AL

City/town on I-59 with hotels
Birmingham: 28 miles


Springville to Trussville: 13 miles

Trussville, AL

City/town on I-59 with hotels
Birmingham: 15 miles


Trussville to Birmingham: 15 miles

Birmingham, AL

Second-largest city in Alabama, where I-59, I-65, I-20 and I-22 come together


Birmingham to Bessemer: 17 miles

Bessemer, AL

City/town on I-59 with hotels
Birmingham: 17 miles
Tuscaloosa: 35 miles


Bessemer to Tuscaloosa: 35 miles

Tuscaloosa, AL

Home of the flagship campus of the University of Alabama system


Tuscaloosa to Meridian: 91 miles

Meridian, MS

City/town on I-59 with hotels
Tuscaloosa: 91 miles


Meridian to Laurel: 58 miles

Laurel, MS

City/town on I-59 with hotels
Tuscaloosa: 149 miles


Laurel to Hattiesburg: 30 miles

Hattiesburg, MS

Home of the University of Southern Mississippi
Tuscaloosa: 179 miles


Hattiesburg to Picayune: 61 miles

Picayune, MS

City/town on I-59 with hotels
Tuscaloosa: 240 miles


Picayune to Slidell: 17 miles

Slidell, LA

The southern terminus of I-59 is at the junction with I-10 and I-12
Tuscaloosa: 257 miles

I-59 States

Alabama
Georgia
Louisiana
Mississippi

Recent Updates

Hampton Inn & Suites Bessemer Birmingham

Hampton Inn on the southern end of the Birmingham metro area gets great reviews

BAGAIL Compression Packing Cubes

Save space and keep things organized when traveling #ad

Holiday Inn Express Westley

A place to stay on one of those long road trips on I-5 through California

Holiday Inn Express Hotel & Suites Pell City

Hotel is on the north side of Pell City, at the town's exit off I-20 in eastern Alabama

Holiday Inn Express & Suites Willcox

Hotel on I-10 in New Mexico, on the long ride from Texas to the Pacific Coast

LUGGEX Carry On

Some seriously manly luggage, for you or the manly man in your life #ad

Fairfield Inn & Suites by Marriott Stony Creek

Comfortable road trip hotel adjacent to I-95 in southern Virginia